Complete Distal Rupture of the Rectus Femoris in an Elite Football Player: A Non-operative Treatment.

Although muscle injuries represent the most frequent injury in professional football, isolated complete distal ruptures of the rectus femoris (RF) muscle are rare, and there is no consensus on their treatment and return to play (RTP). In this article, we report a clinical case of successful non-surgical management of an RF grade 4c muscle injury in a professional football player, in which the athlete was able to RTP 21 weeks after the injury, had no re-injury >1 year after RTP, and is playing at an elite level in the Portuguese Football First League.

Return to Play After the Diagnosis of Reactive Arthritis in a Professional Football Player.

In professional football, most of the injuries are traumatic; however, these athletes may suffer from rheumatologic diseases, that may present as sports-related injuries. Reactive arthritis (ReA) is classified as a sub-group of the spondyloarthritis family and is relatively rare. In this article, we highlight the successful return to play (RTP) process after the ReA diagnosis in an elite football player in the Portuguese first league. The athlete was able to RTP four months and one week after the diagnosis, had no ReA recurrence nor re-injury >8 months after RTP, and is playing at an elite level.

Development of core competencies for field veterinary epidemiology training programs.

A workforce with the adequate field epidemiology knowledge, skills and abilities is the foundation of a strong and effective animal health system. Field epidemiology training is conducted in several countries to meet the increased global demand for such a workforce. However, core competencies for field veterinary epidemiology have not been identified and agreed upon globally, leading to the development of different training curricula. Having a set of agreed core competencies can harmonize field veterinary epidemiology training. The Food and Agriculture Organization of the United Nations (FAO) initiated a collective, iterative, and participative process to achieve this and organized two expert consultative workshops in 2018 to develop core competencies for field veterinary epidemiology at the frontline and intermediate levels. Based on these expert discussions, 13 competencies were identified for the frontline and intermediate levels. These competencies were organized into three domains: epidemiological surveillance and studies; field investigation, preparedness and response; and One Health, communication, ethics and professionalism. These competencies can be used to facilitate the development of field epidemiology training curricula for veterinarians, adapted to country training needs, or customized for training other close disciplines. The competencies can also be useful for mentors and employers to monitor and evaluate the progress of their mentees, or to guide the selection process during the recruitment of new staff.

One health systems strengthening in countries: Tripartite tools and approaches at the human-animal-environment interface.

Unexpected pathogen transmission between animals, humans and their shared environments can impact all aspects of society. The Tripartite organisations-the Food and Agriculture Organization of the United Nations (FAO), the World Health Organization (WHO), and the World Organisation for Animal Health (WOAH)-have been collaborating for over two decades. The inclusion of the United Nations Environment Program (UNEP) with the Tripartite, forming the 'Quadripartite' in 2021, creates a new and important avenue to engage environment sectors in the development of additional tools and resources for One Health coordination and improved health security globally. Beginning formally in 2010, the Tripartite set out strategic directions for the coordination of global activities to address health risks at the human-animal-environment interface. This paper highlights the historical background of this collaboration in the specific area of health security, using country examples to demonstrate lessons learnt and the evolution and pairing of Tripartite programmes and processes to jointly develop and deliver capacity strengthening tools to countries and strengthen performance for iterative evaluations. Evaluation frameworks, such as the International Health Regulations (IHR) Monitoring and Evaluation Framework, the WOAH Performance of Veterinary Services (PVS) Pathway and the FAO multisectoral evaluation tools for epidemiology and surveillance, support a shared global vision for health security, ultimately serving to inform decision making and provide a systematic approach for improved One Health capacity strengthening in countries. Supported by the IHR-PVS National Bridging Workshops and the development of the Tripartite Zoonoses Guide and related operational tools, the Tripartite and now Quadripartite, are working alongside countries to address critical gaps at the human-animal-environment interface.

A mathematical formulation and an NSGA-II algorithm for minimizing the makespan and energy cost under time-of-use electricity price in an unrelated parallel machine scheduling.

In many countries, there is an energy pricing policy that varies according to the time-of-use. In this context, it is financially advantageous for the industries to plan their production considering this policy. This article introduces a new bi-objective unrelated parallel machine scheduling problem with sequence-dependent setup times, in which the objectives are to minimize the makespan and the total energy cost. We propose a mixed-integer linear programming formulation based on the weighted sum method to obtain the Pareto front. We also developed an NSGA-II method to address large instances of the problem since the formulation cannot solve it in an acceptable computational time for decision-making. The results showed that the proposed NSGA-II is able to find a good approximation for the Pareto front when compared with the weighted sum method in small instances. Besides, in large instances, NSGA-II outperforms, with 95% confidence level, the MOGA and NSGA-I multi-objective techniques concerning the hypervolume and hierarchical cluster counting metrics. Thus, the proposed algorithm finds non-dominated solutions with good convergence, diversity, uniformity, and amplitude.

A center experience with lung transplantation for COVID-19 ARDS.

COVID-19 can cause irreversible lung damage from acute respiratory distress syndrome (ARDS), chronic respiratory failure associated with post COVID-19 de novo fibrosis or worsening of an underlying fibrotic lung disease. Pregnant women are at increased risk for invasive mechanical ventilation, extracorporeal membrane oxygenation, and death. The Centers for Disease Control and Prevention reported more than 22,000 hospitalizations and 161 deaths for COVID-19 in pregnant women. Between August 2020 and September 2021, five patients underwent bilateral lung transplant (LT) for COVID-19 ARDS at the Henry Ford Hospital in Detroit, Michigan. De-identified demographics data, clinical characteristics, perioperative challenges, explanted lung pathology, and post-transplant outcomes are described. In post-hospitalization follow-up (median survival 273 days), we see improving endurance and excellent lung function. One patient did not survive to hospital discharge and succumbed to complications 5 months after LT. We report the first cases of bilateral LT in two postpartum women.

Unveiling biogeographical patterns of the ichthyofauna in the Tuichi basin, a biodiversity hotspot in the Bolivian Amazon, using environmental DNA.

To date, more than 2400 valid fish species have been recorded in the Amazon basin. However, some regions remain poorly documented. This is the case in the Beni basin and in particular in one of its main sub-basins, the Tuichi, an Andean foothills rivers flowing through the Madidi National Park in the Bolivian Amazonia. The knowledge of its ichthyological diversity is, however, essential for the management and protection of aquatic ecosystems, which are threatened by the development of infrastructures (dams, factories and cities), mining and deforestation. Environmental DNA (eDNA) has been relatively little used so far in the Amazon basin. We sampled eDNA from water in 34 sites in lakes and rivers in the Beni basin including 22 sites in the Tuichi sub-basin, during the dry season. To assess the biogeographical patterns of the amazonian ichthyofauna, we implemented a metabarcoding approach using two pairs of specific primers designed and developed in our laboratory to amplify two partially overlapping CO1 fragments, one of 185bp and another of 285bp. We detected 252 fish taxa (207 at species level) among which 57 are newly identified for the Beni watershed. Species compositions are significantly different between lakes and rivers but also between rivers according to their hydrographic rank and altitude. Furthermore, the diversity patterns are related to the different hydro-ecoregions through which the Tuichi flows. The eDNA approach makes it possible to identify and complete the inventory of the ichthyofauna in this still poorly documented Amazon basin. However, taxonomic identification remains constrained by the lack of reference barcodes in public databases and does not allow the assignment of all OTUs. Our results can be taken into account in conservation and management strategies and could serve as a baseline for future studies, including on other Andean tributaries.

A Congested Match Schedule Alters Internal Match Load and Affects Salivary Immunoglobulin A Concentration in Youth Soccer Players.

ABSTRACT: Mortatti, AL, Oliveira, RSCd, Pinto, JCBdL, Galvão-Coelho, NL, Almeida, RN, Aoki, MS, and Moreira, A. A congested match schedule alters internal match load and affects salivary immunoglobulin A concentration in youth soccer players. J Strength Cond Res 36(6): 1655-1659, 2022-The aim of this study was to analyze the effects of a congested match schedule (CMS) undertaken after a tapering week, on internal match load (IML) and salivary immunoglobulin A (SIgA) concentration in 12 youth soccer players (16.6 ± 0.5 years; 175 ± 8 cm; 65 ± 8 kg) who performed 4 official matches within a 4-day period. Internal match load was determined using the session-rating of perceived exertion method and the competitive strain (CS) and monotony index (MI) were also determined. Saliva sampling was conducted, before the last training day of a tapering week (training) preceding the CMS, 60 minutes before the first match (match-1), and 22 hours after match 4 (postmatch 4). Salivary immunoglobulin A was analyzed by ELISA. The results of the analysis of variance with repeated measures showed a significant difference for IML across the matches (p < 0.001). A significant reduction in SIgA was observed from prematch 1 to postmatch 4 (p = 0.019). Regarding the change in SIgA (ΔSIgA), 58.3% of the players presented values equal/higher than the minimal detectable change. A large within-individual correlation was observed between ΔSIgA and MI and CS (r = 0.71 and r = 0.72: p < 0.01, respectively). The current findings suggest that youth players participating in a CMS may present a decrease in mucosal immunity function. In addition, data suggest that the MI and CS may be used as valuable markers for monitoring competition load during CMS in youth soccer players.

Effects of Integrative Neuromuscular Training on Motor Performance in Prepubertal Soccer Players.

ABSTRACT: Menezes, GB, Alexandre, DR, Pinto, JC, Assis, TV, Faigenbaum, AD, and Mortatti, AL. Effects of integrative neuromuscular training on motor performance in prepubertal soccer players. J Strength Cond Res 36(6): 1667-1674, 2022-The present study examined the effects of integrative neuromuscular training (INT) on motor performance in prepubertal soccer players. Subjects were randomly assigned to the experimental group (INT; n = 20, age: 8.2 ± 1.2 years; body mass: 28.4 ± 6.4 kg; height: 1.3 ± 0.1 m) or the control group (CON; n = 18, age: 8.5 ± 1.3 years; body mass: 32.8 ± 8.9 kg; height: 1.3 ± 0.1 m). Integrative neuromuscular training program was performed twice per week during the 12-week training intervention. Balance, flexibility, countermovement vertical jump height (CVJH), sprint speed, and change of direction speed (CODS) were assessed in both groups at baseline, sixth week and 12th week. A mixed model repeated measures analysis of variance was used to examine the group changes in performance for each variable. There was a time effect for balance in the INT from pre to 12th weeks (p < 0.001, g = 0.72), and from 6th to 12th weeks (p = 0.005, g = 0.34). An interaction effect for balance was also observed between INT and CON after the 12th week. A time effect in flexibility was observed in INT from baseline to 6th and 12th weeks (p = 0.02; g = 0.45 and p < 0.001; g = 0.71) and from 6 to 12th weeks (p = 0.003; g = 0.24). There was a time effect in CVJH, from baseline to 12th week and from 6th to 12th weeks (p < 0.05; g = 0.34 and g = 0.53, respectively). There was no significant between-group speed performance change. A time effect was found in CODS in INT, but only from baseline to 12th week (p = 0.02; g = 0.31). There were significant improvements in the percent change (Δ%) from baseline to 12 weeks (p < 0.05) for balance, flexibility, and CVJH in INT. These findings indicate that the addition of an INT program to soccer practice can improve selected motor performance skills in prepubertal soccer players.

The Effects of Successive Soccer Matches on the Internal Match Load, Stress Tolerance, Salivary Cortisol and Jumping Performance in Youth Soccer Players.

The study aim was to analyze the effects of successive matches on the internal match load, stress tolerance, salivary cortisol concentration and countermovement vertical jump height in twelve youth soccer players (16.6 ± 0.5 yr; 175 ± 8 cm; 65 ± 8 kg) who performed four official matches within a four day-period with a 24-h recovery interval between the matches. The internal match load, monotony index and competitive strain, as well as stress tolerance were examined. Saliva samples were collected and countermovement vertical jump height was assessed 60 min pre and 30 min post each match; delta of salivary cortisol and countermovement vertical jump height for each match were analyzed. Salivary cortisol was analyzed using an enzyme-linked immunosorbent assay. The results of ANOVA with repeated measures showed no differences between matches for the internal match load (p > 0.05). The scores of the monotony index and competitive strain were 4.3 (±2.3) and 8104 (±6795) arbitrary units, respectively. There was no difference for stress tolerance between matches (p > 0.05). Delta values of salivary cortisol were not different among the assessed matches (F(3,33) = 1.397, p = 0.351, η2: 0.09); however, delta of countermovement vertical jump height decreased from match 1 to match 4 (F(3,33) = 8.64, p < 0.001, η2: 0.44). The current findings suggest that participating in four successive matches, with 24-h of recovery in between, may not lead to changes in stress tolerance and salivary cortisol of youth players, but it may induce a decrease in players' jumping performance after the fourth match.

Differences in Handgrip Strength-Endurance and Muscle Activation Between Young Male Judo Athletes and Untrained Individuals.

Purpose: The aim of this study was to compare strength-endurance handgrip performance and muscle coactivation between judo athletes and untrained young males. Method: The sample was 38 judo athletes and 38 untrained young males, between 12 and 15 years-old. Maturational status was evaluated by age at peak height velocity. A maximal isometric handgrip test (three 5-s repetitions, with 90-s intervals) and an isometric strength-endurance handgrip test (ten 10-s all-out isometric handgrip repetitions, 20-s intervals) was conducted in dominant (D) and nondominant (ND) hands, using a dynamometer with EMG monitor to detect muscle activation. Results: ANCOVA analysis, controlling for maturational status, showed that judo athletes had higher values of maximal absolute (D = 33.6 ± 8.9 kgf vs 29.1 ± 9.0 kgf; ND = 33.8 ± 9.9 kgf vs 28.1 ± 8.1 kgf) and relative strength to body mass (D = 0.64 ± 0.12 kg/kgf vs 0.57 ± 0.13 kg/kgf; ND = 0.64 ± 0.16 kg/kgf vs 0.56 ± 0.14 kg/kgf). Moreover, judo athletes presented lower strength mean fatigue index (33.2 ± 6.9 % vs 37.9 ± 8.7 %) and muscle coactivation (48 ± 19.8 % vs 57.5 ± 22 %), only in the dominant hand, during the isometric strength-endurance handgrip test. During all repetitions of isometric endurance test there were no group or interaction between factors effects for absolute strength, relative strength and muscle coactivation. Conclusion: In summary, judo athletes present higher maximal absolute and relative strength and strength-endurance performance, concomitantly with decreased muscles co-activation (primary in dominant hand) during handgrip tests.

Do heart rate variability is relationed to endurance performance in female futsal players? / A variabilidade da frequência cardíaca está relacionada ao desempenho de resistência em jogadoras de futsal?

abstract The study aimed to verify the correlation between resting heart rate variability (HRVrest) and endurance performance in female futsal players, as well as to evaluate the reliability of this parasympathetic autonomic marker. A total of 16 female futsal players (age: 22 ± 3 years; VO2max: 42.3 ± 2.0 ml.kg-1.min-1) were evaluated during the first week of preseason training. Vagal modulation was evaluated from the HRVrest (i.e., log-transformed root mean square of successive R-R interval differences - Ln-RMSSD) for two consecutive days, while endurance performance was evaluated by the Yo-Yo Intermittent Recovery Test, Level 1 (Yo-Yo IR1). Pearson correlation was used to analyze the relationship between the variables. Strong correlation between the HRVrest index and endurance performance (r = 0.643; p = 0.007). Reliability was tested through the intraclass correlation coefficient, coefficient of variation (CV), and Bland-Altman analysis of the agreement. Furthermore, acceptable repeatability of HRVrest, but with great inter-subject variability (ICC = 0.670, 95%CI = 0.056-0.885, CV = 15.8%). The current study demonstrated a strong correlation between Ln-RMSSD and endurance performance, and despite the acceptable values of intrasubject reliability, HRVrest presented high inter-individual variability in female futsal players.

resumo O objetivo do estudo foi verificar a correlação entre a variabilidade da frequência cardíaca de repouso (VFCRepouso) e o desempenho de resistência em jogadoras de futsal, bem como avaliar a confiabilidade do marcador parassimpático. No total, 16 jogadoras de futsal (idade: 22 ± 3 anos; VO2max: 42.3 ± 2.0 ml.kg-1.min-1) foram avaliadas durante a primeira semana de treinamento da pré-temporada. A modulação vagal foi avaliada a partir da VFC de repouso (isto é, raiz quadrada da média das diferenças sucessivas ao quadrado dos intervalos R-R adjacentes - Ln-RMSSD) por dois dias consecutivos, enquanto o desempenho da resistência foi avaliado pelo Yo-Yo Intermittent Recovery Test, Level 1 (Yo-Yo IR1). A correlação de Pearson foi utilizada para analisar a relação entre as variáveis. A confiabilidade foi testada através do coeficiente de correlação intraclasse, coeficiente de variação e análise de concordância de Bland-Altman. Observou-se uma forte correlação entre o índice de VFCrepouso e o desempenho de endurance (r = 0,643; p = 0,007). Por outro lado, repetibilidade aceitável dos índices de repouso vagal, mas com grande variabilidade interindividual (ICC = 0,670, IC = 0,056-0,885, CV = 15,8%). O presente estudo apresentou forte correlação entre Ln-RMSSD e desempenho de endurance, e mesmo com valores aceitáveis de confiabilidade intrasujeito, a VFC em repouso apresentou alta variabilidade interindividual em jogadoras de futsal.

Uso do celular antes de dormir: um fator com maior risco para sonolência excessiva em adolescentes de escolas militares / Cell phone use before bedtime: a risk factor for excessive sleepiness in adolescents from military schools

OBJETIVO: Investigar a prevalência de sonolência diurna excessiva (SDE) e os fatores associados em adolescentes de escolas militares. MÉTODOS: Participaram 466 adolescentes do ensino médio (15 a 17 anos) de ambos os sexos (230 homens). Os participantes foram entrevistados sobre as características sociodemográficas e sobre a duração de sono (semana e final de semana), adotando-se valores < 8 horas de sono como tempo insuficiente de sono. A SDE foi avaliada com a escala de sonolência de Epworth, na qual os adolescentes que obtivessem escores ≥ 10 apresentavam SDE. RESULTADOS: A prevalência geral de SDE foi de 34,1%. A média de horas de sono foi de 6,9 h (±1,85) em dias da semana e de 8,5 h (±1,96) nos fins de semana. Identificou-se que 60% dos adolescentes apresentaram baixa duração do sono semanal (p = 0,05). Observaram-se, no modelo final de regressão, maiores riscos de SDE nos indivíduos com baixa duração de sono (OR: 1,55; IC de 95%: 1,04-2,31) e que utilizavam o celular antes de dormir (OR: 4,30; IC de 95%: 2,00-9,23). CONCLUSÃO: A SDE foi fortemente associada ao uso de celular antes de dormir. Outros fatores associados são sono insuficiente e estudar em tempo integral. Medidas educacionais, administrativas e de saúde são necessárias para melhorar o sono em adolescentes.

OBJECTIVE: To investigate the prevalence of excessive daytime sleepiness (EDS) and associated factors in adolescents attending military schools. METHODS: 466 high school students (15-17 years old) of both sexes (230 men) participated. Participants were interviewed about sociodemographic characteristics and sleep duration (week and weekend), adopting values < 8 hours of sleep as insufficient sleep time. EDS was assessed with the Epworth Sleepiness Scale; where students with scores ≥ 10 had EDS. RESULTS: The overall prevalence of EDS was 34.1%. The mean for sleep hours was 6.9 h (±1,85) on weekdays and 8.5 h (±1.96) on weekends. It was identified that 60% of the adolescents presented short weekly sleep duration (p = 0.05). In the final regression model, higher EDS risks were observed in those subjects that had a short sleep duration (OR: 1.55; 95% CI: 1.04-2.31) and those that used the cell phone before bedtime (OR: 4.30; 95% CI: 2.00-9.23). CONCLUSION: EDS was strongly associated with cell phone use before bedtime. Other associated factors are insufficient sleep and studying full-time. Educational, administrative and health measures are needed to improve sleep in adolescents.

Efeitos dos jogos reduzidos sobre os marcadores psicofisiológicos de atletas de futsal feminino / Effects of small-sided games on psychophysiological markers of female futsal athletes

O objetivo do estudo foi analisar o efeito da quantidade de balizas em jogos reduzidos no futsal (JRF's) sobre a carga interna e resposta afetiva. Participaram do estudo oito atletas adultas de futsal feminino, que treinavam regularmente cinco vezes por semana. Foram analisadas duas sessões de treinamento: 1) JRF1baliza 4 x 4 com uma baliza para cada equipe; 2) JRF3balizas4 x 4 com três balizas para cada equipe. A ordem dos JRF's foi escolhida de forma randomizada. Para análise da carga interna utilizou-se a escala CR 0-10 de percepção subjetiva de esforço (PSE) e para a resposta afetiva, utilizou-se a escala de sentimento (feeling scale). Utilizou-se o teste t pareado para análise da resposta psicofisiológica, considerando significativo um valor p < 0,05. Em nossos resultados os valores de P SE foram semelhantes entre os JRF's (JRF1baliza: 4,5 ± 1,7 vs. JRF3balizas: 4,4 ± 0,7, p > 0,05) da mesma fo rm a para a resposta afetiva (JRF1baliza: 0,2 ± 0,8 vs. JRF3balizas: 0,1 ± 1,0, p > 0,05), adicionalmente observou-se que os valores de PSE fixaram-se em "um pouco difícil" e a resposta afetiva permaneceu positiva durante ambos os JRF's. Em suma, conclui-se que os JRF1baliza e JRF3balizas obtiveram respostas semelhante nos marcadores psicofisiológicos (PSE e Afeto) em atletas adultas de futsal feminino...(AU)

The aim of this study was to analyze the effect of the number of goals in futsal small-sided games (SSG) on the internal load and affective response. Eight adult female futsal players regularly training five times a week participated in the study. Two training sessions were analyzed: 1) SSG1goal 4 x 4 with one goal for each team; 2) SSG3goal 4 x 4 with three goals for each team. The order of SSG was chosen in a randomized fashion. The CR 0-10 scale of rating of perceived exertion (RPE) was ch o sen to analyze internal load and for the affective response, the feeling scale was used. Paired t test was used t o analyze the psychophysiological response, considering a value p < 0.05. It was observ ed t hat t he RPE values were similar between the SSG (SSG1goal: 4.5 ± 1.7 vs. SSG3goal: 4.4 ± 0.7, p > 0.05) in the same way for affective response (SSG1goal: 0.2 ± 0.8 vs. SSG3goal: 0.1 ± 1.0, p > 0.05), it was further observed that the RPE values were set as "a little difficult" and the values of the Feeling Scale was p o sit iv e durin g bo th SSG. In summary, the SSG1goal and SSG3goal being performed in random order with seven days rest between them, obtained similar responses in the psychophysiological markers in adult female futsal players...(AU)

Pielonefritis xantogranulomatosa secundaria a litiasis obstructiva en un paciente pediátrico / Pyelonephritis Xanthogranulomatous Secundary to Obstructive Lithiasis in Pediatric Patient

Introducción La pielonefritis xantogranulomatosa (XGPN), es una enfermedad inflamatoria crónica del parénquima renal, de rara presentación en pediatría. Su etiología es multifactorial comenzando con un proceso obstructivo del tracto urinario por litiasis e infección hasta el daño renal crónico. Su diagnóstico se logra por sospecha clínica, estudio imagenológico e histopatológico, lo que require tratamiento definitivo en la mayoría con nefrectomía simple. Materiales y métodos Paciente masculino de 4 años de edad con infección de la vía urinaria y dilatación de pelvis y uréter causada por cálculos que genera un proceso inflamatorio crónico y destrucción del parénquima renal. Sin respuesta clínica a tratamiento antibiótico quien requirió manejo en unidad de cuidados intensivos y nefrectomía. Discusión Se presenta entre la cuarta a sexta década de vida, con reportes de caso en edad pediátrica. Cursa con fiebre, dolor abdominal y masa palpable. Puede presentar en cambio de cursar con leucocitosis, anemia y piuria. Estudio radiológico de XGPN se puede apreciar de forma focal o difusa. A la histopatología se evidencia necrosis tisular crónica con macrófagos espumosos en su interior entremezclados con células inflamatorias. El tratamiento definitivo requiere nefrectomía de unidad renal disfuncional. Conclusiones Se presenta el caso de paciente pediátrico con XGPN por obstrucción urinaria litiásica; entidad de baja frecuencia en ese grupo poblacional, requiere una adecuada correlación clínico-imagenológica e histológica para lograr el diagnóstico final y puede ser tratado con manejo médico y quirúrgico.

Introduction Xanthogranulomatous pyelonephritis (XGPN) is a chronic inflammatory disease of the renal parenchyma, rare in pediatrics. Etiology is multifactorial ranging from an obstructive urinary tract process through lithiasis and infection generating chronic kidney amage. Its diagnosis is achieved by clinical suspicion, imaging and histopathology, which requires definitive treatment in the majority with simple nephrectomy Materials and Methods A 4-year-old male patient with urinary tract infection and dilation of the pelvis and ureter caused by calculus that generate a chronic inflammatory process and destruction of the renal parenchyma. No clinical response to antibiotic treatment that required management and intensive care unit and nephrectomy. Discussion It occurs between the fourth and sixth decade of life, with case reports in pediatric age. Patients have fever, abdominal pain and palpable mass. They can occur with leukocytosis, anemia and pyuria. Radiological study of XGPN can be seen in focal or diffuse form. Histopathology looks a chronic tissue necrosis with foamy macrophages and inflammatory cells. Definitive treatment requires nephrectomy of damaged renal unit. Conclusions We report the case of pediatric patients with XGPN due to urinary obstruction of the lithiasis; Low frequency entity in this population group, requires an adequate clinical-imaging and histological correlation to achieve final diagnosis and can be treated with medical and surgical management.

The Hyalella (Crustacea: Amphipoda) species cloud of the ancient Lake Titicaca originated from multiple colonizations.

Ancient lakes are renowned for their exceptional diversity of endemic species. As model systems for the study of sympatric speciation, it is necessary to understand whether a given hypothesized species flock is of monophyletic or polyphyletic origin. Here, we present the first molecular characterization of the Hyalella (Crustacea: Amphipoda) species complex of Lake Titicaca, using COI and 28S DNA sequences, including samples from the connected Small and Large Lakes that comprise Lake Titicaca as well as from a broader survey of southern South American sites. At least five evolutionarily distant lineages are present within Lake Titicaca, which were estimated to have diverged from one another 12-20 MYA. These major lineages are dispersed throughout the broader South American Hyalella phylogeny, with each lineage representing at least one independent colonization of the lake. Moreover, complex genetic relationships are revealed between Lake Titicaca individuals and those from surrounding water bodies, which may be explained by repeated dispersal into and out of the lake, combined with parallel intralacustrine diversification within two separate clades. Although further work in deeper waters will be required to determine the number of species present and modes of diversification, our results strongly indicate that this amphipod species cloud is polyphyletic with a complex geographic history.

One Health Economics to confront disease threats.

Global economic impacts of epidemics suggest high return on investment in prevention and One Health capacity. However, such investments remain limited, contributing to persistent endemic diseases and vulnerability to emerging ones. An interdisciplinary workshop explored methods for country-level analysis of added value of One Health approaches to disease control. Key recommendations include: 1. systems thinking to identify risks and mitigation options for decision-making under uncertainty; 2. multisectoral economic impact assessment to identify wider relevance and possible resource-sharing, and 3. consistent integration of environmental considerations. Economic analysis offers a congruent measure of value complementing diverse impact metrics among sectors and contexts.

Competencies for government veterinary services of the future: Summary of ISVEE 14 Yucatan 2015 roundtable discussion.

This short communication summarizes the strengths and weaknesses of current organisational structures in government veterinary services, as well as future technical, financial and societal challenges and related necessary competencies for government veterinary services of the future as discussed by an expert panel at ISVEE2015. First, participating representatives of veterinary services of diverse geographical backgrounds and statements from the audience confirmed that non-technical skills such as ability to work in teams, adaptability to new environments and situations, social and communication skills are increasingly seen as important. The second challenge faced by veterinary services is related to capacity issues, i.e. to have enough manpower to plan and deliver according to legislation in a period of shrinking budgets. New and emerging diseases can result in sudden, massive increases in the workload of veterinary services. Technical complexity has also increased for some hazards. Staff skills in veterinary services therefore need to be continuously updated, and it is essential to establish cross technical collaboration with other sectors including food safety, public health and environment. ISVEE conferences were seen as an opportunity to provide a global platform to develop skills needed by veterinary services, now and in the future.

Development and Assessment of a Geographic Knowledge-Based Model for Mapping Suitable Areas for Rift Valley Fever Transmission in Eastern Africa.

Rift Valley fever (RVF), a mosquito-borne disease affecting ruminants and humans, is one of the most important viral zoonoses in Africa. The objective of the present study was to develop a geographic knowledge-based method to map the areas suitable for RVF amplification and RVF spread in four East African countries, namely, Kenya, Tanzania, Uganda and Ethiopia, and to assess the predictive accuracy of the model using livestock outbreak data from Kenya and Tanzania. Risk factors and their relative importance regarding RVF amplification and spread were identified from a literature review. A numerical weight was calculated for each risk factor using an analytical hierarchy process. The corresponding geographic data were collected, standardized and combined based on a weighted linear combination to produce maps of the suitability for RVF transmission. The accuracy of the resulting maps was assessed using RVF outbreak locations in livestock reported in Kenya and Tanzania between 1998 and 2012 and the ROC curve analysis. Our results confirmed the capacity of the geographic information system-based multi-criteria evaluation method to synthesize available scientific knowledge and to accurately map (AUC = 0.786; 95% CI [0.730-0.842]) the spatial heterogeneity of RVF suitability in East Africa. This approach provides users with a straightforward and easy update of the maps according to data availability or the further development of scientific knowledge.